国际权威的医学学术期刊American Journal of Respiratory and Critical Care Medicine近日刊登了一篇关于罗马提案：慢性阻塞性肺疾病加重的最新定义和严重程度分类《An Updated Definition and Severity Classification of Chronic Obstructive Pulmonary Disease Exacerbations: The Rome Proposal》。

首先，它依赖于病人对增加的呼吸道症状的主观感受，这种感知因病人而异，并且可以被其他情况(如肺炎、心脏事件或肺栓塞)影响。

其次，它没有将症状与可衡量的病理生理变量联系起来，而这些病理生理变量可以受事件本身影响。

最后，他缺少关于触发事件发展的框架，一个可以帮助区分将ECOPDS从其他具有类似症状进展区分开来。

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